Based on quark and lepton masses, as well as on the CKM mixing pattern, the couplings of Higgs with fermions ( seem to be highly hierarchic. That hierarchy is expected to be due to the severe breaking of an underlying flavour symmetry group.
New improved results on the size of the flavour changing neutral processes collected at LHC are helpful in building New Physics models which encompass the observed since of CP violation and of the hierarchy among various species of quarks and leptons. Most significantly recent LHCb results on b -> s mu mu suggest some tensions with respect to the Standard Model (SM).
Moreover, models which explain these tensions can be handle Dark matter candidates.