Abstract: Overview of high-resolution measurements of space radiation in space with the Timepix ASIC chips from CERN operated in miniaturized radiation cameras from Advacam on board satellites and Cubesats and on board the International Space Station. Review of innovative techniques of radiation detection, particle tracking, quantum-imaging dosimetry and spectral- and composition-characterization of mixed-radiation fields in space/in LEO orbit and in particle radiotherapy environments. Examples of novel scientific experiments and applied research in space and further applications (nuclear physics, environment, cosmic rays, education).