High-mass binary systems involve extreme environments that produce non-thermal emission from radio to gamma rays. Only three types of these systems are known to emit persistent gamma-ray emission: colliding-wind binaries, high-mass X-ray binaries and gamma-ray binaries. This thesis is focused on the radio emission of high-mass binary systems through interferometric observations, and we have explored several of these sources with low- and high-frequency radio observations, and very high-resolution VLBI ones. We have studied two gamma-ray binaries at low frequencies, LS 5039 and LS I +61 303. We have obtained their light-curves and spectra, and determined the physical properties of their radio emitting regions. We have also studied the gamma-ray binary HESS J0632+057 through VLBI observations. A new colliding wind binary, HD 93129A, has been discovered through VLBI and optical observations. Finally, we have conducted radio observations of two sources that were candidates to be gamma-ray binaries.