Despite its remarkable success, the Standard Model (SM) of particle physics does not address key facts revealed by cosmological and astrophysical observations. Until now, no signs of new physics have been discovered in laboratory experiments, leaving unclear what is the path chosen by Nature for the physics beyond the SM (BSM). I will discuss in this talk how indirect signals from Dark Matter (DM) might help us in this challenging "theoretical selection problem", with implications on foundational aspects of BSM physics. I will illustrate this point with possible DM interpretations of recent anomalies in multimessenger observations of energetic radiation of Galactic and extragalactic origin.

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